The concept of depression and why it occurs

　　Depression can be triggered by excessive pressure in life, and if this disease is not relieved and treated in time, the harm is very great. Therefore, in our daily life, we have to understand the concept of this disease and its causes, then we can better prevent, this disease is also a psychological disease, next let the experts for the concept of depression and the causes, give us a detailed introduction.

　　 Disease introduction

　　Depression is a common mood disorder, can be caused by a variety of reasons, with significant and persistent depressed mood as the main clinical features, and depressed mood is not commensurate with its situation, and in severe cases, suicidal thoughts and behavior. Most cases have a tendency to recur, with most episodes resolving, and some may have residual symptoms or become chronic.

　　Manic episodes can occur in at least 10 % of patients with depression, and should then be diagnosed as bipolar disorder. In addition, what we often refer to as depression is actually clinical major depression, which affects 16% of the population at some point in their lives. In addition to the serious emotional and social costs of depression, the economic costs are enormous. According to the World Health Organization, depression has become the world's fourth most prevalent disease and is expected to become the second most prevalent disease after coronary heart disease by 2020.

　　 Causes

　　So far, the etiology and pathogenesis of depression are not clear, and there are no obvious signs and laboratory indicators of abnormality, summarized as the result of the interaction of biological, psychological and social (cultural) factors. Because the cause of depression is currently unknown, there are many hypotheses about it, and some of the more commonly recognized etiological hypotheses include:

　　 (1) Genetic factors:

　　A large sample of population genetic epidemiologic survey shows that the closer the blood relationship with the diseased person, the higher the probability of disease. The probability of first-degree relatives having the disease is much higher than that of other relatives, which is consistent with the general pattern of genetic diseases.

　　 (2) Biochemical factors:

　　Catecholamine hypothesis: mainly refers to the occurrence of depression may be related to the decrease in the concentration of neurotransmitters 5-hydroxytryptamine (5-HT) and norepinephrine (NE) in the synaptic gap of the brain; due to the fact that after the use of many antidepressants, such as selective 5-hydroxytryptamine reuptake inhibitors (SSRIs) or selective 5-hydroxytryptamine and norepinephrine reuptake inhibitors (SNRIs), etc., though the brain synapse gap, although the concentration of these neurotransmitters rises quickly, the antidepressant effect generally takes about 2 weeks to take effect, hence the hypothesis of increased 5-HT and NE receptor sensitivity (hypersensitivity).

　　 (3) Psycho-social factors:

　　A variety of major life events occurring suddenly, or persisting for a long period of time can cause intense or (and) persistent unpleasant emotional experiences, leading to depression.

　　Warm tips, for depression this disease is a psychological disease, we have to prevent this disease in daily life, only to maintain a good state of mind, learn to release the pressure to adjust themselves in order to get a better preventive effect, in addition to the emergence of this disease, we in addition to cooperate with the medication in addition to dietary therapy is also very important, the experts also gave some of the treatment of depression dietary therapy.