What are the main causes of manic depression?

　　Said depression we all know more or less, but there is a kind of depression called manic depression, I believe that we are a little difficult to understand, or by the name of this disease is not clear, manic to give a person's feeling is always bad, and then put together with depression is even more frightening, such a terrible disease in the end how to cause it, I believe that we must be very curious, the following will be introduced to you! What are the main causes of manic depression.

　　1.Neuroendocrine dysfunction

　　There is sufficient evidence to show that manic-depressive psychosis is closely related to the regulation of neuroendocrine function, which is mainly in the hypothalamus-pituitary-adrenal axis and hypothalamus-pituitary-thyroid axis changes.

　　2.Biochemical metabolic abnormalities

　　In patients with manic-depressive psychosis, the activity of norepinephrine in the central nervous system is low, whereas it is relatively increased in the manic phase, indicating that mania and depression are related to the high and low activity of norepinephrine in the brain.

　　3.Genetic factors

　　The prevalence among relatives of patients with manic-depressive psychosis is 10 to 30 times higher than that of the general population, and the closer the blood relationship with the patient, the higher the prevalence. Knowing the causes of depression, patients can treat depression immediately.

　　4.Somatic, psychological and environmental factors

　　Manic-depressive psychosis has psychiatric factors in about half of the patients before the first onset of the disease, but these factors may work only as a condition for the onset of the disease, i.e., as a precipitating factor.

　　After reading the above content I believe that we have a simple understanding of manic depression, triggered by manic depression has many causes, but also can understand that this is a very terrible disease, so we must pay attention to this disease, after the disease must go to the regular hospital for treatment, and strive to get rid of depression as soon as possible.